You must have income from a business.
The trip must be for "business purposes" For example, going to a seminar related to your business, meeting with clients / vendors, visiting your investment properties, or going to an annual meeting with your partners
Pay all of your travel expenses with business card and not with a personal card
Save all of your receipts to evidence the cost of the flight, hotels, cars, and meals
Document the main purpose of the trip. Be as specific as possible
Confirm with your CPA to comply with the specific tax rules
Include your expenses on your tax return as business travel expenses.